Killerbot now owns a copy of Vista (or so I've been told). Poor guy
Currently the general answer to any question starting with "I have this problem under Vista,..." that you'll generally get is:
We don't know, we don't care, we don't do Vista.
The "we don't care" part may not be entirely true, but for the time being, that much has to do. It will probably take several months before we can answer the Vista-related questions without guessing.
That does not mean that Code::Blocks may not run under Vista. It means we simply don't know anything about it, nor have we really tested anything profoundly. What we do know is that Microsoft changed quite a lot things which they previously advocated, and now they claim that they have always discouraged their use. Inhowfar this affects the operation of Code::Blocks, who knows.
Also, we know that the new "security" features as well as the filesystem virtualisation may interfere with a few components, for example plugin installation. However, it may also be that the user does not even notice this, as the worst part of Vista is that it silently replaces things behind your back in a typical Microsoft-like manner, leaving you hardly any way of actually knowing.
We do have a report from one user who has successfully compiled Code::Blocks using Code::Blocks under Vista. On the other hand side, it has been reported that for example MinGW does not work under Vista at all (again, this is hearsay, no idea whether it is true).