I copy the ./configure line, I use on debian, if I build wxWidgets myself (it's sometimes necessary, for debugging purposes, even if this line is not for debugging, it was to compile wx2.8 from svn).
../configure --prefix=/home/jens/wx-tmp --with-zlib=sys --disable-reserved-virtual --with-gtk --enable-mediactrl --enable-sound --with-sdl --enable-display --enable-geometry --enable-graphics_ctx --with-libtiff=sys --with-libjpeg=sys --with-libpng=sys --enable-unicode --with-opengl --disable-stl --enable-aui --disable-debug
Monolithic is useful on windows, but normally not needed on linux (if you use wx-config).