I do regularly, but I am in the minority. The reason I do is because i also use c/c++ quite a bit, for which there is no peer for C::B (biased of course). C::B has a lot of nice features that make it a good general purpose editor.
With just a little work you can set up python projects. (There are no scripted language project templates in C::B by default yet)
Alternatively use the FileManager plugin and Tools+ plugin to view your script directory and configure launchers for your favorite python (or any other) tools. Arguably this is more pythonic.
I started work on a python debugger. It is functional.
At some point I had implemented a plugin that did code checks and highlighted errors. That could be resurrected
I have wanted to work on code completion and browsing tools for quite a few years but it is a big job. I will get to it one day.
I should put together a wiki entry...
Other alternatives:
1. Pyscripter - multi platform, lots of good features. Often recommend to colleagues starting out with python
2. Eclipse - too heavy for my taste but works for some
3. Gedit with lots of plugins - Linux only last I checked
Honorable mention: stanis python editor
There are commercial offerings as well (some free) but I won't recommend those.
