wxWidgets* => C:\src\wxWidgets, C:\src\boost
wxWidgetsProject1 => E:\wxWidgets, E:\boost
codeblocks => E:\wxWidgets, E:\codeblocks\devel
I think CB save the path of "C++ parser options" in cbp file is not good....that's exactly why global compiler variables (GCV) were introduced. Read about this concept in the Wiki. It will resolve your issues and even more... ;-)